Vit C5 alcalina

Descriere

Contribuie la prevenirea apariției afecțiunilor degenerative (Parkinson, Alzheimer, scleroză multiplă, sindrom metabolic – diabet etc.)

Ingrediente:

Vitamina C Alcalină – (L-  ascorbat de sodiu)

Soc – flori (Sambucus nigra)

Turmeric – rădăcină (Curcuma longa)

Astragalus – rădăcină (Astragalus membranaceus)

Ceai verde – frunze (Camellia sinensis), extract apos 4:1 cu 40% polifenoli

Efecte:

• Contribuie la reducerea proceselor inflamatorii de la nivelul articulațiior (artrită, artrită reumatoida);
• Contribuie la apoptoza și inhibarea dezvoltării celulelor tumorale, reducerea cancerului;
• Contribuie la reducerea efectelor secundare în cazul chimioterapiei, radioterapiei;
• Susține funcționarea normală a sistemului imunitar,  îmbunatatirea funcționarii rinichilor și a sistemului cardiovascular;
• Contribuie la protejarea ADN-ului față de agresiunea factorilor perturbatori;
• Contribuie la menținerea în bune condiții a pereților vaselor de sânge a elasticității venelor și arterelor, reducerea plăcilor de aterom
• Contribuie la favorizarea absorbției substanțelor nutritive și la stimularea proceselor de regenerare a țesuturilor;
• Contribuie la procesele de reglare a metabolismului glucidic și lipidic și la scaderea nivelului de colesterol LDL din sânge;
• Contribuie la îmbunătățirea funcționarii sistemului digestiv, a ficatului și vezicii biliare;

Vitamina C (L–ascorbat de sodiu)

• Sodium ascorbate (SA) and l-ascorbic acid (AA) as modifiers of burn affected skin – A comparative analysis. Spectrochim Acta A Mol Biomol Spectrosc. 2019 Feb 15;209:55-61. doi: 10.1016/j.saa.2018.10.021. Epub 2018 Oct 16. Pielesz A, Ślusarczyk C, Biniaś D, Bobiński R.
• Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014 Sep;75(3):173-82. doi: 10.1016/j.jdermsci.2014.05.011. Epub 2014 Jun 11. Hinek A, Kim HJ, Wang Y, Wang A, Mitts TF.
• Evaluation of Uracil, Sodium Ascorbate, and Rosiglitazone as Promoters of Urinary Bladder Transitional Cell Carcinomas in Male Sprague-Dawley Rats. Toxicol Pathol. 2018 Feb;46(2):147-157. doi: 10.1177/0192623318756004. Tirmenstein M, Janovitz E, Dorr T, Song Y, Chen SJ, Granaldi K, Chadwick KD, Mangipudy R, Graziano M, Attalla B, Haile S, Czajkowski M, Foster JR, Bergholm AM, Billger M, Söderberg M.
• Dopamine-Induced Ascorbate Release From Retinal Neurons Involves Glutamate Release, Activation of AMPA/Kainate Receptors and Downstream Signaling Pathways Camila Cabral Portugal, Thaísa Godinho da Encarnação, Ivan Domith, Alexandre dos Santos Rodrigues, Nádia Almeida de Oliveira, Renato Socodato, and Roberto Paes-de-Carvalho PMCID: PMC6521073PMID: 31143097Front Neurosci. 2019; 13: 453.Published online 2019 May 9. doi: 10.3389/fnins.2019.00453
• Colon cleansing efficacy and safety with 1 L NER1006 versus 2 L polyethylene glycol + ascorbate: a randomized phase 3 trial. Bisschops R, Manning J, Clayton LB, Ng Kwet Shing R, Álvarez-González M; MORA Study Group. Endoscopy. 2019 Jan;51(1):60-72. doi: 10.1055/a-0638-8125. Epub 2018 Jul 19.
• Restoration of 5‐hydroxymethylcytosine by ascorbate blocks kidney tumour growth Guangzhe Ge, Ding Peng, Ziying Xu, Bao Guan, Zijuan Xin, Qun He, Yuanyuan Zhou, Xuesong Li, Liqun Zhou and Weimin Ci PMCID: PMC6073201 PMID: 29959161 EMBO Rep. 2018 Aug; 19(8): e45401.Published online 2018 Jun 28. doi: 10.15252/embr.201745401

Soc (Sambucus nigra)

• The Content of Selected Minerals, Bioactive Compounds, and the Antioxidant Properties of the Flowers and Fruit of Selected Cultivars and Wildly Growing Plants of Sambucus nigraL. Młynarczyk K, Walkowiak-Tomczak D, Staniek H, Kidoń M, Łysiak GP. Molecules. 2020 Feb 17;25(4). pii: E876. doi: 10.3390/molecules25040876.
• A Green Extraction Process for Polyphenols from Elderberry (Sambucus nigra) Flowers Using Deep Eutectic Solvent and Ultrasound-Assisted Pretreatment. Kaltsa O, Lakka A, Grigorakis S, Karageorgou I, Batra G, Bozinou E, Lalas S, Makris DP. Molecules. 2020 Feb 19;25(4). pii: E921. doi: 10.3390/molecules25040921.
• Molecular characterization of a novel Aureusvirus infecting elderberry (Sambucus nigraL.). Šafářová D, Vavroušková K, Candresse T, Navrátil M. PLoS One. 2018 Aug 16;13(8):e0200506. doi: 10.1371/journal.pone.0200506. eCollection 2018.
• Concentration of Bioactive Compounds from Elderberry (Sambucus nigraL.) Juice by Nanofiltration Membranes. Tundis R, Loizzo MR, Bonesi M, Sicari V, Ursino C, Manfredi I, Conidi C, Figoli A, Cassano A. Plant Foods Hum Nutr. 2018 Aug 8. doi: 10.1007/s11130-018-0686-x.
• Identification of Peptides in Flowers of Sambucus nigrawith Antimicrobial Activity against Aquaculture Pathogens. Álvarez CA, Barriga A, Albericio F, Romero MS, Guzmán F. Molecules. 2018 Apr 27;23(5). pii: E1033. doi: 10.3390/molecules23051033.
• Lectin binding patterns in normal, dysplastic and Helicobacter pylori infected gastric mucosa. Vernygorodskyi S, Shkolnikov V, Suhan D. Exp Oncol. 2017 Jul;39(2):138-140.
• The kinetics of thermal degradation of polyphenolic compounds from elderberry ( Sambucus nigraL.) extract. Oancea AM, Onofrei C, Turturica M, Bahrim G, Rapeanu G, Stanciuc N. Food Sci Technol Int. 2018 Jun;24(4):361-369. doi: 10.1177/1082013218756139. Epub 2018 Feb 6.
• Antiviral potential of medicinal plants against HIV, HSV, influenza, hepatitis, and coxsackievirus: A systematic review. Akram M, Tahir IM, Shah SMA, Soc (Sambucus nigra) Mahmood Z, Altaf A, Ahmad K, Munir N, Daniyal M, Nasir S, Mehboob H. Phytother Res. 2018 May;32(5):811-822. doi: 10.1002/ptr.6024. Epub 2018 Jan 22. Review.
• Polyphenolic content, antiradical activity, stability and microbiological quality of elderberry (Sambucus nigra L.) extracts. Pliszka B.Acta Sci Pol Technol Aliment. 2017 Oct-Dec;16(4):393-401. doi: 10.17306/J.AFS.0523. PMID:29241318
• Interfering With Lipid Raft Association: A Mechanism to Control Influenza Virus Infection By Sambucus Nigra. Shahsavandi S, Ebrahimi MM, Hasaninejad Farahani A. Iran J Pharm Res. 2017 Summer;16(3):1147-1154.
• Chlorogenic acid isomer contents in 100 plants commercialized in Brazil. Meinhart AD, Damin FM, Caldeirão L, da Silveira TFF, Filho JT, Godoy HT. Food Res Int. 2017 Sep;99(Pt 1):522-530. doi: 10.1016/j.foodres.2017.06.017.
• Plant-made virus-like particles bearing influenza hemagglutinin (HA) recapitulate early interactions of native influenza virions with human monocytes/macrophages. Makarkov AI, Chierzi S, Pillet S, Murai KK, Landry N, Ward BJ. Vaccine. 2017 Aug 16;35(35 Pt B):4629-4636. doi: 10.1016/j.vaccine.2017.07.012.
• Sorafenib induced alteration of protein glycosylation in hepatocellular carcinoma cells. Liu T, Liu R, Zhang S, Guo K, Zhang Q, Li W, Liu Y. Oncol Lett. 2017 Jul;14(1):517-524. doi: 10.3892/ol.2017.6177.
• Sorafenib induced alteration of protein glycosylation in hepatocellular carcinoma cells. Liu T, Liu R, Zhang S, Guo K, Zhang Q, Li W, Liu Y. Oncol Lett. 2017 Jul;14(1):517-524. doi: 10.3892/ol.2017.6177.
• Label-free chronopotentiometric glycoprofiling of prostate specific antigen using sialic acid recognizing lectins. Belicky S, Černocká H, Bertok T, Holazova A, Réblová K, Paleček E, Tkac J, Ostatná V. Bioelectrochemistry. 2017 Oct;117:89-94. doi: 10.1016/j.bioelechem.2017.06.005. Epub 2017 Jun 19.
• Lectin array and glycogene expression analyses of ovarian cancer cell line A2780 and its cisplatin-resistant derivate cell line A2780-cp. Zhao R, Qin W, Qin R, Han J, Li C, Wang Y, Xu C. Clin Proteomics. 2017 May 23;14:20. doi: 10.1186/s12014-017-9155-z. eCollection 2017.
• Polyphenols Pattern and Correlation With Antioxidant Activities of Berries Extracts From Four Different Populations of Sicilian Sambucus Nigra L Manuela Mandrone, Beatrice Lorenzi, Antonella Maggio, Tommaso La Mantia, Monica Scordino, Maurizio Bruno, Ferruccio Poli Nat Prod Res. 2014;28(16):1246-53. doi: 10.1080/14786419.2014.898147. Epub 2014 Mar

Turmeric (Curcuma longa)

• Usha T, Pradhan S, Goyal AK, Dhivya S, Kumar HPP, Singh MK, Joshi N, Basistha BC, Murthy KRS, Selvaraj S, Middha SK. Molecular Simulation-based Combinatorial Modeling and Antioxidant Activities of Zingiberaceae Family Rhizomes.Pharmacogn Mag. 2017 Oct;13(Suppl 3):S715-S722. doi: 10.4103/pm.pm_82_17. Epub 2017 Oct 11. PMID:29142438 Free PMC Article https://www.ncbi.nlm.nih.gov/pubmed/29142438
• Naqvi A, Malasoni R, Gupta S, Srivastava A, Pandey RR, Dwivedi AK. <i>In Silico</i> and <i>In Vitro</i> Anticancer Activity of Isolated Novel Marker Compound from Chemically Modified Bioactive Fraction from <i>Curcuma longa</i> (NCCL). Pharmacogn Mag. 2017 Oct;13(Suppl 3):S640-S644. doi: 10.4103/pm.pm_23_17. Epub 2017 Jul 18. PMID:29142426 Free PMC Article https://www.ncbi.nlm.nih.gov/pubmed/29142426
• Mou S, Zhou Z, He Y, Liu F, Gong L. Curcumin inhibits cell proliferation and promotes apoptosis of laryngeal cancer cells through Bcl-2 and PI3K/Akt, and by upregulating miR-15a. Oncol Lett. 2017 Oct;14(4):4937-4942. doi: 10.3892/ol.2017.6739. Epub 2017 Aug 10. PMID: 29085504 Free PMC Article https://www.ncbi.nlm.nih.gov/pubmed/29085504
• Curcumin inhibits the proliferation and induces apoptosis in HT-29 cell lines through a reactive oxygen species (ROS)-dependent mechanism. Wang J, Qi L, Mei L, Wu Z.Pak J Pharm Sci. 2017 Sep;30 (5):1671-1677. PMID:29084689
• Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure.Liu Z, Cui C, Xu P, Dang R, Cai H, Liao D, Yang M, Feng Q, Yan X, Jiang P. Front Neurosci. 2017 Oct 4;11:558. doi: 10.3389/fnins.2017.00558. eCollection 2017. PMID:29046626 Free PMC Article https://www.ncbi.nlm.nih.gov/pubmed/29046626
• Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1. Zang S, Tang Q, Dong F, Liu H, Li L, Guo F, Pan X, Lin H, Zeng W, Cai Z, Zhong Q, Zang N, Zang L. Oncol Rep. 2017 Dec;38(6):3583-3591. doi: 10.3892/or.2017.6028. Epub 2017 Oct 12. PMID: 29039582 https://www.ncbi.nlm.nih.gov/pubmed/29039582
• http://ayurvedic-medica.ro/site/produsele-noastre/sanohelp/64-proprietatile-turmericului-fac-radioterapia-si-chimioterapia
• Curcuma longa Extract Exerts a Myorelaxant Effect on the Ileum and Colon in a Mouse Experimental Colitis Model, Independent of the Anti-Inflammatory Effect, Rita Aldini, Roberta Budriesi, Giulia Roda, Matteo Micucci, Pierfranco Ioan, Antonia D’Errico-Grigioni, Alessandro Sartini, Elena Guidetti, Margherita Marocchi, Monica Cevenini, Francesca Rosini, Marco Montagnani, Alberto Chiarini, Giuseppe Mazzella PLoS One. 2012; 7(9): e44650. Published online 2012 Sep 12. doi: 10.1371/journal.pone.0044650, PMCID: PMC3440350
• Hepatic protection and anticancer activity of curcuma: A potential chemopreventive strategy against hepatocellular carcinoma, YAN LI, XUE SHI, JINGWEN ZHANG, XIANG ZHANG, ROBERT C.G. MARTIN, Int J Oncol. 2014 Feb; 44(2): 505–513. Published online 2013 Nov 21. doi: 10.3892/ijo.2013.2184, PMCID: PMC3898719 • De Novo Transcriptome Assembly (NGS) of Curcuma longa L. Rhizome Reveals Novel Transcripts Related to Anticancer and Antimalarial Terpenoids, Ramasamy S. Annadurai, Ramprasad Neethiraj, Vasanthan Jayakumar, Anand C. Damodaran, Sudha Narayana Rao, Mohan A. V. S. K. Katta, Sreeja Gopinathan, Santosh Prasad Sarma, Vanitha Senthilkumar, Vidya Niranjan, Ashok Gopinath, Raja C. Mugasimangalam, PLoS One. 2013; 8(2): e56217. Published online 2013 Feb 28. doi: 10.1371/journal.pone.0056217, PMCID: PMC3585318 • Inhibition of lung cancer cells A549 and H460 by curcuminoid extracts and nanoemulsions prepared from Curcuma longa Linnaeus, Hong-Bin Chang, Bing-Huei Chen, Int J Nanomedicine. 2015; 10: 5059–5080. Published online 2015 Aug 5. doi: 10.2147/IJN.S87225, PMCID: PMC4531038 • Combinatorial cytotoxic effects of Curcuma longa and Zingiber officinaleon the PC-3M prostate cancer cell line, Kesava Rao V. Kurapati, Thangavel Samikkannu, Dakshayani B. Kadiyala, Saiyed M. Zainulabedin, Nimisha Gandhi, Sadhana S. Sathaye, Manohar A. Indap, Nawal Boukli, Jose W. Rodriguez, Madhavan P.N. Nair, J Basic Clin Physiol Pharmacol. Author manuscript; available in PMC 2015 Sep 7., Published in final edited form as: J Basic Clin Physiol Pharmacol. 2012; 23(4): 139–146.doi: 10.1515/jbcpp-2012-0021, PMCID: PMC4561547 • Effect of Curcuma longa and Ocimum sanctum on myocardial apoptosis in experimentally induced myocardial ischemic-reperfusion injury, Ipseeta Mohanty, Dharamvir Singh Arya, Suresh Kumar Gupta, BMC Complement Altern Med. 2006; 6: 3. Published online 2006 Feb 19. doi: 10.1186/1472-6882-6-3, PMCID: PMC1397864 • Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa, Grace G. L. Yue, Ben C. L. Chan, Po-Ming Hon, Mavis Y. H. Lee, Kwok-Pui Fung, Ping-Chung Leung, Clara B. S. Lau, Food Chem Toxicol. Author manuscript; available in PMC 2011 Aug 1., Published in final edited form as: Food Chem Toxicol. 2010 Aug–Sep; 48(8-9): 2011–2020. Published online 2010 May, 9. doi: 10.1016/j.fct.2010.04.039, PMCID: PMC2910176 • Hepatoprotective and immunomodulatory properties of aqueous extract of Curcuma longa in carbon tetra chloride intoxicated Swiss albino mice, Mahuya Sengupta, Gauri Dutta Sharma, Biswajit Chakraborty, Asian Pac J Trop Biomed. 2011 Jun; 1(3): 193–199. doi: 10.1016/S2221-1691(11)60026-9, PMCID: PMC3609192 • A Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity, Minakshi Rana, Preeti Maurya, Sukka S. Reddy, Vishal Singh, Hafsa Ahmad, Anil K. Dwivedi, Madhu Dikshit, Manoj K. Barthwal, Front Pharmacol. 2016; 7: 223. Published online 2016 Jul 25. doi: 10.3389/fphar.2016.00223, PMCID: PMC4959270
• Immunostimulatory activities of polysaccharide extract isolated from Curcuma longa, Grace G. L. Yue, Ben C. L. Chan, Po-Ming Hon, Kwok-Pui Fung, Ping-Chung Leung, Clara B. S. Lau, Int J Biol Macromol. Author manuscript; available in PMC 2011 Oct 1., Published in final edited form as: Int J Biol Macromol. 2010 Oct 1; 47(3): 342–347. Published online 2010 Jun 1.doi: 10.1016/j.ijbiomac.2010.05.019, PMCID: PMC2917522
• Liposomal Formulation of Turmerone-Rich Hexane Fractions from Curcuma longa Enhances Their Antileishmanial Activity, Ana Claudia F. Amaral, Luciana A. Gomes, Jefferson Rocha de A. Silva, José Luiz P. Ferreira, Aline de S. Ramos, Maria do Socorro S. Rosa, Alane B. Vermelho, Igor A. Rodrigues, Biomed Res Int. 2014; 2014: 694934. Published online 2014 J, 18. doi: 10.1155/2014/694934, PMCID: PMC4087288
• Evaluation of phenolic profile, antioxidant and anticancer potential of two main representants of Zingiberaceae family against B164A5 murine melanoma cells, Corina Danciu, Lavinia Vlaia, Florinela Fetea, Monica Hancianu, Dorina E Coricovac, Sorina A Ciurlea, Codruta M Soica, Iosif Marincu, Vicentiu Vlaia, Cristina A Dehelean, Cristina Trandafirescu, Biol Res. 2015; 48(1): 1. Published online 2015 Jan 12. doi: 10.1186/0717-6287-48-1, PMCID:PMC44172
• ,,Protective effect of curcumin and vitamin C each alone and in combination on cisplatin-induced sperm abnormalities in male albino rats” Sabha Elsayed Elballat http://www.sciencedirect.com/science/article/pii/S2090989616300662
• ,,Curcumin mitigates lithium-induced thyroid dysfunction by modulating antioxidant status, apoptosis and inflammatory cytokines” Sanaa M. Abd El-Twab, Manal Abdul-Hamid http://www.sciencedirect.com/science/article/pii/S209098961630022
• ,,Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in Cancer Cells.” Ooko E, Kadioglu O, Greten HJ, Efferth T. Front Pharmacol. 2017 Feb 2;8:38. doi: 10.3389/fphar.2017.00038. PMID: 28210221 https://www.ncbi.nlm.nih.gov/pubmed/28210221
• ,,Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.” James W Daily, Mini Yang, Sunmin Park, J Med Food. 2016 Aug ;19(8):717-29. PMID: 27533649 http://www.greenmedinfo.com/article/these-rcts-provide-scientific-evidence-supports-efficacy-turmeric-extract
• ,,Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers.” G Shoba, D Joy, T Joseph, M Majeed, R Rajendran, P S Srinivas, Planta Med. 1998 May;64(4):353-6. PMID: 9619 120 http://www.greenmedinfo.com/article/bioavailability-study-piperine
• ,,Possible action mechanism for curcumin in pre-cancerous lesions based on serum and salivary markers of oxidative stress.” Balwant Rai, Jasdeep Kaur, Reinhilde Jacobs, Jaipaul Singh, J Oral Sci. 2010;52(2):251-6. PMID: 20587949 http://www.greenmedinfo.com/article/curcumin-exhibits-anti-pre-cancer-activity • ,,Curcumin positively modulates blood lipids and reduces lipid peroxidation.” J Miquel, A Bernd, J M Sempere, J Díaz-Alperi, A Ramírez, Arch Gerontol Geriatr. 2002 Feb;34(1):37-46. PMID: 14764309http://www.greenmedinfo.com/article/curcumin-positively-modulates-blood-lipids-and-reduces-lipid-peroxidation • ,, Curcumin prevents DNA damage and enhances the repair potential in a chronically arsenic-exposed human population in West Bengal, India.”, Madhumita Roy, Dona Sinha, Sutapa Mukherjee, Jaydip Biswas, Eur J Cancer Prev. 2011 Mar;20(2):123-31. PMID: 21332098 http://www.greenmedinfo.com/article/curcumin-reduces-arsenic-induced-dna-damage-human-subjects • ,,Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal.” Jaydip Biswas, Dona Sinha, Sutapa Mukherjee, Soumi Roy, Maqsood Siddiqi, Madhumita Roy, Hum Exp
• Toxicol. 2010 Jan 7. Epub 2010 Jan 7. PMID: 20056736 http://www.greenmedinfo.com/article/curcumin-protects-dna-damage-chronically-arsenic-exposed-population-west-bengal • ,,Curcuminoids with piperine may be used as a safe and effective add on to standard antidepressants in patients with major depressive disorders.” Yunes Panahi, Roghayeh Badeli, Gholam-Reza Karami, Amirhossein Sahebkar, Phytother Res. 2015 Jan ;29(1):17-21. Epub 2014 Aug 4. PMID: 25091591http://www.greenmedinfo.com/article/curcuminoids-piperine-may-be-used-safe-and-effective-add-standard • ,,Dosage Study: Turmeric extract can be administered safely to patients at doses of up to 2.2 g daily, equivalent to 180 mg of curcumin.”, R A Sharma, H R McLelland, K A Hill, C R Ireson, S A Euden, M M Manson, M Pirmohamed, L J Marnett, A J Gescher, W P Steward, Clin Cancer Res. 2001 Jul;7(7):1894-900. PMID: 11448902http://www.greenmedinfo.com/article/dosage-study-turmeric-extract • K B Soni, R Kuttan, Indian J Physiol Pharmacol. 1992 Oct;36(4):273-5. PMID: 1291482 http://www.greenmedinfo.com/article/oral-curcumin-positively-modulates-blood-lipid-levels-and-lipid-peroxidation Oral curcumin positively modulates blood lipid levels and lipid peroxidation. • ,,Curcumin could modulate hepatocyte epithelial-mesenchymal transition implicated in treatment of liver fibrosis.”, Desong Kong, Feng Zhang, Jiangjuan Shao, Li Wu, Xiaoping Zhang, Li Chen, Yin Lu, Shizhong Zheng, Lab Invest. 2015 Aug 24. Epub 2015 Aug 24. PMID: 26302188 http://www.greenmedinfo.com/article/curcumin-could-modulate-hepatocyte-epithelial-mesenchymal-transition • Haris P, Mary V, Aparna P, Dileep KV, Sudarsanakumar C. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Mar 15;175:155-163. doi: 10.1016/j.saa.2016.11.049. Epub 2016 Dec 5. https://www.ncbi.nlm.nih.gov/pubmed/28033562 A comprehensive approach to ascertain the binding mode of curcumin with DNA. • Curcumin: An effective adjunct in patients with statin-associated muscle symptoms? Sahebkar A, Saboni N, Pirro M, Banach M. J Cachexia Sarcopenia Muscle. 2017 Feb;8(1):19-24. doi: 10.1002/jcsm.12140. Epub 2016 Sep 22. https://www.ncbi.nlm.nih.gov/pubmed/27897416

Astragalus (Astragalus membranaceus)

„Astragalus | Universitatea din Maryland Medical Center” . Umm.edu. 2013-05-07.

www.greenmedinfo.com/substance/astragalus

https://www.rroij.com/open-access/cyclo astragenoltelomeres-activator Cycloastragenol (Telomeres Activator) and its relation with Cancer

http://www.greenmedinfo.com/article/compound-found-within-astragalus-called cycloastragenol

Zargary, plante medicinale A.. Cincea Edition.Tehran: Teheran Universitatea Publicatii 1990; pp. 312-314

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Harley, CB, si colab. (2011). „Un produs telomerazei activator naturale, ca parte a unui program de intretinere a sanatatii” . Rejuvenation Research

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Rios, JL; PG Waterman (1998). „O revizuire a farmacologie si toxicologie de Astragalus”. Fitoterapie Cercetare

Jung SM, Schumacher HR, Kim H., Kim M., Lee SH, Pessler F. „Reducerea inflamatie determinate de urati indusa de cristale din extracte de radacina de plante medicinale traditionale orientale: Altitudine de prostaglandine nivel D2” artrita Cercetare si Terapie 2007 9: 4 Numar articol R64

• ,,Dietary safety of cycloastragenol from Astragalus spp.: Subchronic toxicity and genotoxicity studies” Food and Chemical Toxicology, Volume 64, February 2014, Pages 322-334 Nancy J. Szabo
• ,,Microbial transformation of Astragalus sapogenins using Cunninghamella blakesleeanaNRRL 1369 andGlomerella fusarioidesATCC 9552”, Journal of Molecular Catalysis B: Enzymatic, Volume 115, May 2015, Pages 29-34, Erdal Bedir, Ceyda Kula, Özlem Öner, Melis Altas, Özgür Tağ, Gaye Öngen
• https://www.jstage.jst.go.jp/article/dmpk/27/6/27_DMPK-11-RG-160/_pdf ,,Pharmacokinetic Evidence on the Contribution of Intestinal Bacterial Conversion to Beneficial Effects of Astragaloside IV, a Marker Compound of Astragali Radix, in Traditional Oral Use of the Herb”
• Drug Metabolism and Pharmacokinetics, Volume 27, Issue 6, 2012, Pages 586-597 Rui-Na Zhou, Yue-Lin Song, Jian-Qing Ruan, Yi-Tao Wang, Ru Yan
• Reversal of P-glycoprotein-mediated multidrug resistance of human hepatic cancer cells by Astragaloside II.” Can Huang, Dujuan Xu, Quan Xia, Peipei Wang, Chao Rong, Yong Su, J Pharm Pharmacol. 2012 Dec ;64(12):1741-50. Epub 2012 Jun 8. PMID: 23146037
• Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.” Steven Russell Fauce, Beth D Jamieson, Allison C Chin, Ronald T Mitsuyasu, Stan T Parish, Hwee L Ng, Christina M Ramirez Kitchen, Otto O Yang, Calvin B Harley, Rita B Effros, J Immunol. 2008 Nov 15;181(10):7400-6. PMID: 18981163
• Reversal of P-glycoprotein-mediated multidrug resistance of human hepatic cancer cells by Astragaloside II.” Can Huang, Dujuan Xu, Quan Xia, Peipei Wang, Chao Rong, Yong Su, J Pharm Pharmacol. 2012 Dec ;64(12):1741-50. Epub 2012 Jun 8. PMID: 23146037Ceai verde (Camellia sinensis)
• Heiss, Mary Lou; Heiss, Robert J. (2007). The story of tea: a cultural history and drinking guide. Ten Speed Press. pp. 179–185. ISBN 1-58008-745-0.
• „CURRENT SITUATION AND MEDIUM-TERM OUTLOOK”. INTERGOVERNMENTAL GROUP ON TEA, UN Food and Agriculture Organization. May 2008. p. 9.
• Cabrera C, Artacho R, Giménez R (April 2006). „Beneficial effects of green tea–a review”. Journal of American College of Nutrition 25 (2): 79–99. text integral.
• Maron DJ, Lu GP, Cai NS, et al. (June 2003). „Cholesterol-lowering effect of a theaflavin-enriched green tea extract: a randomized controlled trial”. Arch. Intern. Med. 163 (12): 1448–53.text.
• „Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans”. Vol. 87, No. 3. American Journal of Clinical Nutrition. March 2008. pp. 778–784. Abstract.
• Emad Al-Dujaili, Jon-Paul Bradley, Suzana Almoosawi & Lorna Fyfe (2009). „Effects of green tea consumption on blood pressure, total cholesterol, body weight and fat in healthy volunteers”. Endocrine Abstracts 20: P470.Abstract.
• Gradišar et al., (2007) Green Tea Catechins Inhibit Bacterial DNA Gyrase by Interaction with Its ATP Binding Site;text.
• Zhang, M; Huang, J; Xie, X; Holman, CD (2009). „Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women.”. International Journal of Cancer 124 (6): 1404–8.doi:10.1002/ijc.24047. PMID 19048616.
• „Green Tea Catechins and Their Oxidative Protection in the Rat Eye.”. Vol. 58, No. 3. Journal of Agricultural and Food Chemistry. February 2010. pp. 1523–1534. text. Retrieved 2010-02-19.
• About.com. The History of Tea – Tea Bags and Makers
• Sartippour MR, Pietras R, Marquez-Garban DC, et al. (December 2006). „The combination of green tea and tamoxifen is effective against breast cancer”. Carcinogenesis 27 (12): 2424–33. text.„Dulloo et al Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.”.
• BBC news – 17 March 2009 – green tea may have the power to ward off breast cancer
• Sueoka N, Suganuma M, Sueoka E, et al. (April 2001). „A new function of green tea: prevention of lifestyle-related diseases”. Ann. N. Y. Acad. Sci. 928: 274–80. text.
• Kuriyama S, Shimazu T, Ohmori K, et al. (September 2006). „Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study”. JAMA 296 (10): 1255–65. text.
  Polyphenols: Potential Future Arsenals in the Treatment of Diabetes. Solayman M, Ali Y, Alam F, Islam MA, Alam N, Khalil MI, Gan SH. Curr Pharm Des. 2016;22(5):549-65. Review. PMID:26601968 https://www.ncbi.nlm.nih.gov/pubmed/26601968Natural Products for the Treatment of Type 2 Diabetes Mellitus. Ríos JL, Francini F, Schinella GR. Planta Med. 2015 Aug;81(12-13):975-94. doi: 10.1055/s-0035-1546131. Epub 2015 Jul 1. Review. PMID:26132858 https://www.ncbi.nlm.nih.gov/pubmed/26132858

  GreenHYPERLINK „https://www.ncbi.nlm.nih.gov/pubmed/28664072” tea and type 2 diabetes. Park JH, Bae JH, Im SS, Song DK. Integr Med Res. 2014 Mar;3(1):4-10. doi: 10.1016/j.imr.2013.12.002. Epub 2013 Dec 14. Review. PMID:28664072 Free PMC Article https://www.ncbi.nlm.nih.gov/pubmed/28664072

  CoffeeHYPERLINK „https://www.ncbi.nlm.nih.gov/pubmed/24071782” and tea: perks for health and longevity? Bhatti SK, O’Keefe JH, Lavie CJ. Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):688-97. doi: 10.1097/MCO.0b013e328365b9a0. Review.

  PMID: 24071782 https://www.ncbi.nlm.nih.gov/pubmed/24071782

  CoffeeHYPERLINK „https://www.ncbi.nlm.nih.gov/pubmed/21631956” and tea consumption in relation to inflammation and basal HYPERLINK

  „https://www.ncbi.nlm.nih.gov/pubmed/21631956″glucoseHYPERLINK „https://www.ncbi.nlm.nih.gov/pubmed/21631956” metabolism in a multi-ethnic Asian population: a cross-sectional study. Rebello SA, Chen CH, Naidoo N, Xu W, Lee J, Chia KS, Tai ES, van Dam RM. Nutr J. 2011 Jun 2;10:61. doi: 10.1186/1475-2891-10-61.

  PMID: 21631956 Free PMC Article https://www.ncbi.nlm.nih.gov/pubmed/21631956

  Green Tea Blocks HIV in Test Tubes

  Rodríguez-Caso C, Rodríguez-Agudo D, Sánchez-Jiménez F, Medina MA (August 2003). „Green tea epigallocatechin-3-gallate is an inhibitor of mammalian histidine decarboxylase”. Cell. Mol. Life Sci. 60 (8): 1760–3. text.

  Lambert JD, Sang S, Yang CS (April 2007). „Possible controversy over dietary polyphenols: benefits vs risks”.Chem. Res. Toxicol. 20 (4): 583–5. text.

  Strick et al.; Strissel, PL; Borgers, S; Smith, SL; Rowley, JD (2000). „Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia.”. Proc. Natl. Acad. Sci. USA 97 (9): 4790–4795. abstract.

  Kaijun Niu et al (2009). „Green tea consumption is associated with depressive symptoms in the elderly”. Am J Clin Nutr. 90 (6): 1615–22. text.

  Golden, E.; Lam, PY; Kardosh, A; Gaffney, KJ; Cadenas, E; Louie, SG; Petasis, NA; Chen, TC et al. (2009). „Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors.”.Blood 113 (23): 5927–5937.

  Neith, Katie. „Green tea blocks benefits of cancer drug, study finds”. text.

  Sarma DN, Barrett ML, Chavez ML, et al. (2008). „Safety of green tea extracts : a systematic review by the US Pharmacopeia”. Drug Saf 31 (6): 469–84. text.

  Master Lam Kam Cheun et al. (2002). The way of tea. Gaia Books. ISBN 1856751430.

  John C, Evans, Tea in China: The History of China’s National Drink. Greenwood Press, 1992.

  Green Tea (an overview from the University of Maryland Medical Center)

  Green Tea and Body Shape (overview from the Lipton Institute of Tea)

  Green Tea’s cancer fighting potential (Audio interview).